Application of gene therapy in auditory system diseases

  • Chunjiang Wei Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China
  • Weijia Kong Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China
  • Zuhong He Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China
Keywords: Gene therapy, Hearing, Transfection vector, Auditory diseases, Inner ear

Abstract

How to prevent and treat auditory related diseases through genetic intervention is a hotspot in the field of hearing research in recent years. With the development of molecular biology, molecular genetics, genetic engineering, etc., especially, gene regulation has made a major breakthrough in the research of inner ear hair cell regeneration in recent years, which may provide us with a novel and efficient way to treat auditory related diseases. This review includes the latest research on gene therapy in hereditary deafness, drug deafness, aging-related hearing loss, and noise-related hearing loss.

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Published
2020-01-02
How to Cite
Wei, C., Kong, W., & He, Z. (2020). Application of gene therapy in auditory system diseases. STEMedicine, 1(1), e17. https://doi.org/10.37175/stemedicine.v1i1.17
Section
Review articles